Sting1^em1Nyan
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sting1^em1Nyan
• Name: stimulator of interferon response cGAMP interactor 1; endonuclease-mediated mutation 1, Nan Yan
• MGI ID: MGI:7312195
• Gene: Sting1 Location: Chr18:35866732-35873607 bp, - strand Genetic Position: Chr18, 19.23 cM, cytoband B3
• Alliance: Sting1^em1Nyan page

Mutation origin

• Strain of Origin: BALB/cNctr-Npc1^m1N/J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting produced a null allele. (J:326430)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sting1 Mutation: 45 strains or lines available

References

• Original: J:326430 Chu TT, et al., Tonic prime-boost of STING signalling mediates Niemann-Pick disease type C. Nature. 2021 Aug;596(7873):570-575
• All: 1 reference(s)