Thpo^em1Suda
Endonuclease-mediated Allele Detail

Summary

• Symbol: Thpo^em1Suda
• Name: thrombopoietin; endonuclease-mediated mutation 1, Toshio Suda
• MGI ID: MGI:7311553
• Synonyms: Thpo^fl
• Gene: Thpo Location: Chr16:20543204-20553261 bp, - strand Genetic Position: Chr16, 12.51 cM
• Alliance: Thpo^em1Suda page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR/Cas9 technology was used to flank exons 2 and 3 with loxP sites. (J:326356)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Thpo Mutation: 23 strains or lines available

References

• Original: J:326356 O'Neill A, et al., Thrombopoietin maintains cell numbers of hematopoietic stem and progenitor cells with megakaryopoietic potential. Haematologica. 2021 Jul 1;106(7):1883-1891
• All: 2 reference(s)