Cant1^em1Tfric
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cant1^em1Tfric
• Name: calcium activated nucleotidase 1; endonuclease-mediated mutation 1, Tatsuya Furuichi
• MGI ID: MGI:7310358
• Gene: Cant1 Location: Chr11:118297115-118309912 bp, - strand Genetic Position: Chr11, 83.15 cM
• Alliance: Cant1^em1Tfric page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/cas9 mediated recombination created a 10 bp deletion in exon 3. (J:326326)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cant1 Mutation: 26 strains or lines available

References

• Original: J:326326 Kodama K, et al., CANT1 deficiency in a mouse model of Desbuquois dysplasia impairs glycosaminoglycan synthesis and chondrocyte differentiation in growth plate cartilage. FEBS Open Bio. 2020 Jun;10(6):1096-1103
• All: 1 reference(s)