Mir204^tm1Liam
Targeted Allele Detail

Summary

• Symbol: Mir204^tm1Liam
• Name: microRNA 204; targeted mutation 1, Mingyu Liang
• MGI ID: MGI:7310317
• Gene: Mir204 Location: Chr19:22727969-22728036 bp, + strand Genetic Position: Chr19, 17.26 cM
• Alliance: Mir204^tm1Liam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326324
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• The entire 68 bp pre-miRNA was deleted by homologous recombination. (J:326324)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir204 Mutation: 2 strains or lines available

References

• Original: J:326324 Cheng Y, et al., Endogenous miR-204 Protects the Kidney against Chronic Injury in Hypertension and Diabetes. J Am Soc Nephrol. 2020 Jul;31(7):1539-1554
• All: 1 reference(s)