Asb12^em1Mngx
Endonuclease-mediated Allele Detail

Summary

• Symbol: Asb12^em1Mngx
• Name: ankyrin repeat and SOCS box-containing 12; endonuclease-mediated mutation 1, Mingxi Liu
• MGI ID: MGI:7310252
• Gene: Asb12 Location: ChrX:94513807-94601593 bp, - strand Genetic Position: ChrX, 41.99 cM, cytoband C1
• Alliance: Asb12^em1Mngx page

Mutation origin

• Strain of Origin: CD-1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• CRISPR-targeting of exon 4 inserted 1 bp resulting in a truncated protein of 123 amino acids. (J:324158)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Asb12 Mutation: 2 strains or lines available

References

• Original: J:324158 Zhang R, et al., Testis-enriched Asb12 is not required for spermatogenesis and fertility in mice. Transl Androl Urol. 2022 Feb;11(2):168-178
• All: 1 reference(s)