Otud3^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Otud3^em1Cya
• Name: OTU domain containing 3; endonuclease-mediated mutation 1, Cyagan Biosciences
• MGI ID: MGI:7309143
• Synonyms: Otud3^em1Cd
• Gene: Otud3 Location: Chr4:138622690-138641256 bp, - strand Genetic Position: Chr4, 70.57 cM, cytoband D3
• Alliance: Otud3^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a knockout allele by deleting exons 2-3 (5690 bp deletion). (J:326054)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Otud3 Mutation: 23 strains or lines available

References

• Original: J:326054 Cai X, et al., Opposing effects of deubiquitinase OTUD3 in innate immunity against RNA and DNA viruses. Cell Rep. 2022 Jun 7;39(10):110920
• All: 1 reference(s)