Tmprss2^{em1(TMPRSS2)Gpt}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tmprss2^{em1(TMPRSS2)Gpt}
• Name: transmembrane protease, serine 2; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:7307648
• Synonyms: Tmprss2^{em1Cin(hTMPRSS2)}
• Gene: Tmprss2 Location: Chr16:97365882-97412395 bp, - strand Genetic Position: Chr16, 57.53 cM, cytoband C2
• Alliance: Tmprss2^{em1(TMPRSS2)Gpt} page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Tmprss2^{em1(TMPRSS2)Gpt} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TMPRSS2 (7113)

  Tmprss2

  (MGI:1354381)

• CRISPR-targeting replaced the coding sequence in exon 2 with the human gene sequence. (J:293217)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmprss2 Mutation: 56 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 1 reference(s)