Smn1^em1(SMN2)Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Smn1^em1(SMN2)Gpt
• Name: survival motor neuron 1; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:7306524
• Synonyms: Smn1^{em1Cin(Smn1-hSMN2-PolyA)}
• Gene: Smn1 Location: Chr13:100261360-100274198 bp, + strand Genetic Position: Chr13, 52.99 cM, cytoband D1/D2.1
• Alliance: Smn1^em1(SMN2)Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Smn1^em1(SMN2)Gpt expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SMN2 (6607)

  Smn1	(MGI:109257)

• CRISPR-targeting inserted at the start codon the human coding sequence. (J:293217)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smn1 Mutation: 87 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 1 reference(s)