Siglec15^{em1(SIGLEC15)Gpt}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Siglec15^{em1(SIGLEC15)Gpt}
• Name: sialic acid binding Ig-like lectin 15; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:7306101
• Synonyms: Siglec15^{em1Cin(hSIGLEC15)}
• Gene: Siglec15 Location: Chr18:78086829-78100610 bp, - strand Genetic Position: Chr18, 52.43 cM
• Alliance: Siglec15^{em1(SIGLEC15)Gpt} page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Siglec15^{em1(SIGLEC15)Gpt} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SIGLEC15 (284266)

  Siglec15

  (MGI:3646642)

• Mutation details: CRISPR-targeting replaced the endogenous sequence in exons 1 through part of exon 4 encoding the transmembrane domain with the corresponding human gene sequence resulting in a fusion protein. (J:293217)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Siglec15 Mutation: 23 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 1 reference(s)