Iqcn^em5Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Iqcn^em5Gpt
• Name: IQ motif containing N; endonuclease-mediated mutation 5, GemPharmatech Co., Ltd
• MGI ID: MGI:7300903
• Synonyms: Iqcn^em5Cd5237
• Gene: Iqcn Location: Chr8:71156106-71170299 bp, + strand Genetic Position: Chr8, 34.15 cM
• Alliance: Iqcn^em5Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting introduced a coding region modification (del5237). Exons 2 and 3 were deleted using CRISPR/Cas9 genome editing technology. The 5237 bp deletion region contains the start codon, which resulted in disruption of protein expression and function. (J:293217, J:338184)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Iqcn Mutation: 24 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 2 reference(s)