Havcr2^{tm1(HAVCR2)Gpt}
Targeted Allele Detail

Summary

• Symbol: Havcr2^{tm1(HAVCR2)Gpt}
• Name: hepatitis A virus cellular receptor 2; targeted mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:7300137
• Synonyms: Havcr2^tm1(hHAVCR2)
• Gene: Havcr2 Location: Chr11:46345762-46372082 bp, + strand Genetic Position: Chr11, 27.9 cM
• Alliance: Havcr2^{tm1(HAVCR2)Gpt} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:293217
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: BALB/cJGpt

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Havcr2^{tm1(HAVCR2)Gpt} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  HAVCR2 (84868)

  Havcr2

  (MGI:2159682)

• Mutation details: CRISPR-targeting replaced exons 1 through 5 with the corresponding human gene sequence, producing a Humanized sequence signal peptide, extracellular domain, and transmembrane domain. (J:293217)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Havcr2 Mutation: 35 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 1 reference(s)