About   Help   FAQ
Btkem3Gpt
Endonuclease-mediated Allele Detail
Summary
Symbol: Btkem3Gpt
Name: Bruton agammaglobulinemia tyrosine kinase; endonuclease-mediated mutation 3, GemPharmatech Co., Ltd
MGI ID: MGI:7296048
Synonyms: Btkem1Cin(R28C)
Gene: Btk  Location: ChrX:133443085-133484319 bp, - strand  Genetic Position: ChrX, 56.18 cM
Alliance: Btkem3Gpt page
Mutation
origin
Strain of Origin:  C57BL/6JGpt
Mutation
description
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsCRISPR-targeting inserted the mutation that results in the amino acid substitution of arginine with cysteine at position 28 (R28C). (J:293217)
Inheritance:    Not Specified
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Btk Mutation:  22 strains or lines available
References
Original:  J:293217 GemPharmatech, GemPharmatech Website. 2020;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/05/2026
MGI 6.24
The Jackson Laboratory