Paxip1^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Paxip1^em1Bcgen
• Name: PAX interacting (with transcription-activation domain) protein 1; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:7293342
• Synonyms: Ptip^f
• Gene: Paxip1 Location: Chr5:27945078-27996689 bp, - strand Genetic Position: Chr5, 13.23 cM, cytoband A3
• Alliance: Paxip1^em1Bcgen page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of the 5'UTR and a second loxP site downstream of exon 1 via CRISPR/Cas9 technology. (J:325947)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Paxip1 Mutation: 48 strains or lines available

References

• Original: J:325947 Wang Q, et al., PTIP governs NAD(+) metabolism by regulating CD38 expression to drive macrophage inflammation. Cell Rep. 2022 Mar 29;38(13):110603
• All: 2 reference(s)