Grin2a^em3Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Grin2a^em3Smoc
• Name: glutamate receptor, ionotropic, NMDA2A (epsilon 1); endonuclease-mediated mutation 2, Shanghai Model Organisms Center
• MGI ID: MGI:7293336
• Synonyms: Grin2a^{em1(flox)Smoc}, Grin2a^flox
• Gene: Grin2a Location: Chr16:9385762-9813424 bp, - strand Genetic Position: Chr16, 5.28 cM
• Alliance: Grin2a^em3Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR/Cas9 technology flanked exon 2 with loxP sites. (J:325946)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Grin2a Mutation: 67 strains or lines available

References

• Original: J:325946 Zhou J, et al., NMDA receptor-dependent prostaglandin-endoperoxide synthase 2 induction in neurons promotes glial proliferation during brain development and injury. Cell Rep. 2022 Mar 29;38(13):110557
• All: 3 reference(s)