Ttk^tm1Smoc
Targeted Allele Detail

Summary

• Symbol: Ttk^tm1Smoc
• Name: Ttk protein kinase; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7293033
• Synonyms: Ttk^tm1Smoc
• Gene: Ttk Location: Chr9:83716742-83754442 bp, + strand Genetic Position: Chr9, 45.61 cM
• Alliance: Ttk^tm1Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:307590
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct flanked exons 6-8 with loxP sites and inserted an FRT-flanked neomycin resistance cassette. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene. (J:238766, J:307590)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ttk Mutation: 54 strains or lines available

Notes

Mice are distributed on a mixed background (B6;129S).

References

• Original: J:307590 Fang Q, et al., The essential roles of Mps1 in spermatogenesis and fertility in mice. Cell Death Dis. 2021 May 24;12(6):531
• All: 2 reference(s)