Trp53^em1(rox)Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trp53^em1(rox)Smoc
• Name: transformation related protein 53; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7292986
• Synonyms: Trp53^em1(rox)Smoc
• Gene: Trp53 Location: Chr11:69471185-69482699 bp, + strand Genetic Position: Chr11, 42.83 cM, cytoband B2-C
• Alliance: Trp53^em1(rox)Smoc page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: These mice carry rox sites flanking exon 5-7 of Trp53 gene. When crossed with a Dre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Trp53 gene. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Trp53 Mutation: 232 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)