Trem2^{em4(TREM2)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trem2^{em4(TREM2)Smoc}
• Name: triggering receptor expressed on myeloid cells 2; endonuclease-mediated mutation 4, Shanghai Model Organisms Center
• MGI ID: MGI:7292959
• Synonyms: Trem2^{em4(hTREM2)Smoc}
• Gene: Trem2 Location: Chr17:48653429-48659304 bp, + strand Genetic Position: Chr17, 23.99 cM, cytoband C
• Alliance: Trem2^{em4(TREM2)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Trem2^{em4(TREM2)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TREM2 (54209)

  Trem2

  (MGI:1913150)

• The endogenous mouse Trem2 gene was replaced by human TREM2 gene.. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trem2 Mutation: 65 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)