Tlr8^{tm3(TLR8)Smoc}
Targeted Allele Detail

Summary

• Symbol: Tlr8^{tm3(TLR8)Smoc}
• Name: toll-like receptor 8; targeted mutation 3, Shanghai Model Organisms Center
• MGI ID: MGI:7292818
• Synonyms: Tlr8^{tm3(hTLR8)Smoc}
• Gene: Tlr8 Location: ChrX:166025692-166047325 bp, - strand Genetic Position: ChrX, 78.29 cM, cytoband F5
• Alliance: Tlr8^{tm3(TLR8)Smoc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Tlr8^{tm3(TLR8)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TLR8 (51311)

  Tlr8	(MGI:2176887)

• The endogenous mouse Tlr7 and Tlr8 gene was replaced by human TLR7 and TLR8 gene. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tlr8 Mutation: 9 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)