Sorl1^em3Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sorl1^em3Smoc
• Name: sortilin-related receptor, LDLR class A repeats-containing; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
• MGI ID: MGI:7292528
• Synonyms: Sorl1^{em1(flox)Smoc}, Sorl1^em1Smoc
• Gene: Sorl1 Location: Chr9:41876016-42035593 bp, - strand Genetic Position: Chr9, 23.55 cM, cytoband B
• Alliance: Sorl1^em3Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: These mice carry loxP sites flanking exon 5 of Sorl1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Sorl1 gene. While Sorl1-Flox(Stock No.NM-CKO-210174) mice carrying the loxP sites flanking exon 6 of Sorl1 gene. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sorl1 Mutation: 133 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)