Sirt1^tm1Smoc
Targeted Allele Detail

Summary

• Symbol: Sirt1^tm1Smoc
• Name: sirtuin 1; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7292330
• Synonyms: Sirt1^{tm1(flox)Smoc}
• Gene: Sirt1 Location: Chr10:63154784-63174814 bp, - strand Genetic Position: Chr10, 32.57 cM
• Alliance: Sirt1^tm1Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: These mice carry loxP sites flanking exon3 of Sirt1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Sirt1 gene. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sirt1 Mutation: 83 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 3 reference(s)