Sirpa^{tm2(SIRPA)Smoc}
Targeted Allele Detail

Summary

• Symbol: Sirpa^{tm2(SIRPA)Smoc}
• Name: signal-regulatory protein alpha; targeted mutation 2, Shanghai Model Organisms Center
• MGI ID: MGI:7292329
• Synonyms: Sirpa^{tm2(hSIRPA)Smoc}
• Gene: Sirpa Location: Chr2:129434755-129474148 bp, + strand Genetic Position: Chr2, 63.19 cM, cytoband F3
• Alliance: Sirpa^{tm2(SIRPA)Smoc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Sirpa^{tm2(SIRPA)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SIRPA (140885)

  Sirpa

  (MGI:108563)

• Mutation details: The endogenous mouse Sirpa gene was replaced by human SIRPA gene . While hSIRPA (Stock No.NM-HU-00119) have been pulled from shelves for some reasons. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sirpa Mutation: 37 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)