Siglece^{em4(SIGLECE)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Siglece^{em4(SIGLECE)Smoc}
• Name: sialic acid binding Ig-like lectin E; endonuclease-mediated mutation 4, Shanghai Model Organisms Center
• MGI ID: MGI:7292316
• Synonyms: Siglece^{em1(hSIGLECE)Smoc}
• Gene: Siglece Location: Chr7:43300494-43309585 bp, - strand Genetic Position: Chr7, 28.25 cM, cytoband B2
• Alliance: Siglece^{em4(SIGLECE)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Siglece^{em4(SIGLECE)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SIGLEC9 (27180)

  Siglece

  (MGI:1932475)

• Mutation details: The endogenous mice Siglece gene was replaced by human SIGLEC8 gene. While hSIGLEC8(2)(Stock No.NM-HU-210033) mice function similarly to hSIGLEC8 mice,for more detailed information please contact our technical advisor. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Siglece Mutation: 31 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)