Npc1^em2Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Npc1^em2Smoc
• Name: NPC intracellular cholesterol transporter 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
• MGI ID: MGI:7291363
• Synonyms: Npc1^{em2(flox)Smoc}
• Gene: Npc1 Location: Chr18:12322749-12369457 bp, - strand Genetic Position: Chr18, 6.15 cM
• Alliance: Npc1^em2Smoc page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: These mice carry loxP sites flanking exon 9 of Npc1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Npc1 gene. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Npc1 Mutation: 72 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)