Ms4a1^{tm2(MS4A1)Smoc}
Targeted Allele Detail

Summary

• Symbol: Ms4a1^{tm2(MS4A1)Smoc}
• Name: membrane-spanning 4-domains, subfamily A, member 1; targeted mutation 2, Shanghai Model Organisms Center
• MGI ID: MGI:7291159
• Synonyms: Ms4a1^{tm2(hCD20)Smoc}
• Gene: Ms4a1 Location: Chr19:11227043-11243513 bp, - strand Genetic Position: Chr19, 8.19 cM, cytoband B
• Alliance: Ms4a1^{tm2(MS4A1)Smoc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Ms4a1^{tm2(MS4A1)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MS4A1 (931)

  Ms4a1

  (MGI:88321)

• Mutation details: Extracellular and transmembrane region of the endogenous mouse Ms4a1 gene was replaced by corresponding region of human CD20 gene. While hCD20(Stock No.NM-HU-190068) mice function similarly to hCD20(2) mice,for more detailed information please contact our technical advisor. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ms4a1 Mutation: 24 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)