Esr1^em3Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Esr1^em3Smoc
• Name: estrogen receptor 1 (alpha); endonuclease-mediated mutation 3, Shanghai Model Organisms Center
• MGI ID: MGI:7289550
• Synonyms: Esr1^{em3(flox)Smoc}
• Gene: Esr1 Location: Chr10:4561989-4955633 bp, + strand Genetic Position: Chr10, 2.03 cM
• Alliance: Esr1^em3Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: These mice carry loxP sites flanking exon 4 of Esr1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Esr1 gene.While Esr1-Flox(2)(Stock No.NM-CKO-200175) mice carrying the loxP sites flanking exon 3 of Esr1 gene. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Esr1 Mutation: 69 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)