Btla^{em2(BTLA)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Btla^{em2(BTLA)Smoc}
• Name: B and T lymphocyte associated; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
• MGI ID: MGI:7288539
• Synonyms: Btla^{em2(hBTLA)Smoc}
• Gene: Btla Location: Chr16:45043121-45073258 bp, + strand Genetic Position: Chr16, 29.52 cM
• Alliance: Btla^{em2(BTLA)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Btla^{em2(BTLA)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  BTLA (151888)

  Btla	(MGI:2658978)

• Mutation details: Extracellular domain of mouse Btla gene was replaced by human BTLA gene. While hBTLA mice(Stock No.NM-HU-18014) have been pulled from shelves for some reasons. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Btla Mutation: 29 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)