Axl^tm1(AXL)Smoc
Targeted Allele Detail

Summary

• Symbol: Axl^tm1(AXL)Smoc
• Name: AXL receptor tyrosine kinase; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7288415
• Synonyms: Axl^{em1(hAXL)Smoc}
• Gene: Axl Location: Chr7:25456698-25488130 bp, - strand Genetic Position: Chr7, 14.02 cM, cytoband A3-B1
• Alliance: Axl^tm1(AXL)Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Axl^tm1(AXL)Smoc expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  AXL (558)

  Axl	(MGI:1347244)

• The endogenous mouse Axl gene was replaced by human AXL gene. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Axl Mutation: 58 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)