Angptl3^{em1(ANGPTL3)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Angptl3^{em1(ANGPTL3)Smoc}
• Name: angiopoietin-like 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7288257
• Synonyms: Angptl3^{em1(hANGPTL3)Smoc}
• Gene: Angptl3 Location: Chr4:98919191-98926429 bp, + strand Genetic Position: Chr4, 45.6 cM
• Alliance: Angptl3^{em1(ANGPTL3)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Angptl3^{em1(ANGPTL3)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ANGPTL3 (27329)

  Angptl3

  (MGI:1353627)

• Mutation details: The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(3)(Stock No.NM-HU-210037) mice function similarly to hANGPTL3(2) mice, for more detailed information please contact our technical advisor. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Angptl3 Mutation: 34 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)