Ace2^{em3(ACE2)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ace2^{em3(ACE2)Smoc}
• Name: angiotensin converting enzyme 2; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
• MGI ID: MGI:7288066
• Synonyms: Ace2^{em3(hACE2)Smoc}
• Gene: Ace2 Location: ChrX:162922338-162971414 bp, + strand Genetic Position: ChrX, 76.12 cM, cytoband F5
• Alliance: Ace2^{em3(ACE2)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Ace2^{em3(ACE2)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ACE2 (59272)

  Ace2	(MGI:1917258)

• A human ACE2-flag-Wpre-pA expression cassette was knocked into the Ace2 gene start codon site. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ace2 Mutation: 72 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 2 reference(s)