Nlrx1^tm1Tsc
Targeted Allele Detail

Summary

• Symbol: Nlrx1^tm1Tsc
• Name: NLR family member X1; targeted mutation 1, Jurg Tschopp
• MGI ID: MGI:7287520
• Gene: Nlrx1 Location: Chr9:44164014-44179896 bp, - strand Genetic Position: Chr9, 24.84 cM
• Alliance: Nlrx1^tm1Tsc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:203095
• Parent Cell Line: iTL IC1 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The first four coding exons were replaced with a neomycin selection cassette. (J:203095)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nlrx1 Mutation: 39 strains or lines available

References

• Original: J:203095 Rebsamen M, et al., NLRX1/NOD5 deficiency does not affect MAVS signalling. Cell Death Differ. 2011 Aug;18(8):1387
• All: 2 reference(s)