Ash1l^em2Jsgu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ash1l^em2Jsgu
• Name: ASH1 like histone lysine methyltransferase; endonuclease-mediated mutation 2, Ji-Song Guan
• MGI ID: MGI:7282309
• Gene: Ash1l Location: Chr3:88857929-88986682 bp, + strand Genetic Position: Chr3, 39.01 cM
• Alliance: Ash1l^em2Jsgu page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated an 11 bp deletion in exon 2. (J:324978)

Expression

In Mice Carrying this Mutation:

3 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ash1l Mutation: 139 strains or lines available

References

• Original: J:324978 Zhu Tau, et al., Histone methyltransferase Ash1L mediates activity-dependent repression of neurexin-1alpha. Sci Rep. 2016 May 27;6:26597
• All: 4 reference(s)