Ash1l^em1Jsgu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ash1l^em1Jsgu
• Name: ASH1 like histone lysine methyltransferase; endonuclease-mediated mutation 1, Ji-Song Guan
• MGI ID: MGI:7282308
• Synonyms: Ash1l^fl
• Gene: Ash1l Location: Chr3:88857929-88986682 bp, + strand Genetic Position: Chr3, 39.01 cM
• Alliance: Ash1l^em1Jsgu page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 2 was flanked by loxP sites via CRISPR/Cas9 technology. (J:324893)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ash1l Mutation: 139 strains or lines available

References

• Original: J:324893 Yan Y, et al., ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder. Neuron. 2022 Jan 20
• All: 1 reference(s)