Dcx
Endonuclease-mediated Allele Detail
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Symbol: |
Dcx |
Name: |
doublecortin; endonuclease-mediated mutation 2, Itaru Imayoshi |
MGI ID: |
MGI:7282229 |
Synonyms: |
Dcxem2(flpo)Inot, Dcx-T2A-FLPo |
Gene: |
Dcx Location: ChrX:142638838-142716307 bp, - strand Genetic Position: ChrX, 64.89 cM
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Alliance: |
Dcx page
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Strain of Origin: |
Not Specified
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Allele Type: |
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Endonuclease-mediated (Recombinase) |
Mutation: |
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Insertion
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Dcx expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: Using CRISPR/cas9 technology, the mouse Dcx gene colus was targeted to insert a T2A-FLPo expression cassette into the exon 7 just upstream of the stop codon.
(J:314171)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Dcx
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Dcx Mutation: |
18 strains or lines available
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Original: |
J:314171 Inoue YU, et al., An Optimized Preparation Method for Long ssDNA Donors to Facilitate Quick Knock-In Mouse Generation. 7 new recombinases (including the one already entered), and 5 different reporter alleles. Cells. 2021 Apr 30;10(5) |
All: |
1 reference(s) |
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