Rnf212^em1Amp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rnf212^em1Amp
• Name: ring finger protein 212; endonuclease-mediated mutation 1, Alberto M Pendas
• MGI ID: MGI:7281855
• Synonyms: Rnf212^-
• Gene: Rnf212 Location: Chr5:108877156-108922848 bp, - strand Genetic Position: Chr5, 53.24 cM
• Alliance: Rnf212^em1Amp page

Mutation origin

• Strain of Origin: (C57BL/6J x CBA/J)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated a 142 bp deletion encompassing sequences in the end of exon 1, including the ATG start codon, and the start of intron 1 (GRCm39:chr5:108922731-108922872). (J:303558)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf212 Mutation: 11 strains or lines available

References

• Original: J:303558 Felipe-Medina N, et al., A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1. Elife. 2020 Aug 26;9:e56996
• All: 1 reference(s)