Wdfy3^tm1.1Ayama
Targeted Allele Detail

Summary

• Symbol: Wdfy3^tm1.1Ayama
• Name: WD repeat and FYVE domain containing 3; targeted mutation 1.1, Ai Yamamoto
• MGI ID: MGI:7280945
• Synonyms: Wdfy3^delta, Wdfy3^tm1.1Cmn
• Gene: Wdfy3 Location: Chr5:101980822-102217787 bp, - strand Genetic Position: Chr5, 48.95 cM
• Alliance: Wdfy3^tm1.1Ayama page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238334
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6J)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: LoxP sites were inserted to flank exon 5. Cre-mediated recombination in the germline resulted in the deletion of exon 5 and some flanking intronic sequence. (J:238334)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wdfy3 Mutation: 212 strains or lines available

References

• Original: J:238334 Dragich JM, et al., Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain. Elife. 2016 Sep 20;5:e14810
• All: 1 reference(s)