Axin2^tm1Yaz
Targeted Allele Detail

Summary

• Symbol: Axin2^tm1Yaz
• Name: axin 2; targeted mutation 1, Yi Arial Zeng
• MGI ID: MGI:7279280
• Synonyms: Axin2-mGFP
• Gene: Axin2 Location: Chr11:108811175-108841609 bp, + strand Genetic Position: Chr11, 71.83 cM
• Alliance: Axin2^tm1Yaz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:304293
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6 and 129

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The targeting vector is designed to insert a membrane targeted green fluorescent protein (mGFP) sequence, fused to a polyadenylation signal, just downstream of the translational start site in exon 2. An FRT-flanked puromycin resistance (puro) cassette is inserted downstream of exon 2. (J:304293)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Axin2 Mutation: 44 strains or lines available

References

• Original: J:304293 Wang J, et al., Endothelial Wnts control mammary epithelial patterning via fibroblast signaling. Cell Rep. 2021 Mar 30;34(13):108897
• All: 1 reference(s)