Atg16l1^tm3.1Umr
Targeted Allele Detail

Summary

• Symbol: Atg16l1^tm3.1Umr
• Name: autophagy related 16 like 1; targeted mutation 3.1, Ulrike Mayer
• MGI ID: MGI:7279135
• Synonyms: Atg16L1^fl
• Gene: Atg16l1 Location: Chr1:87683730-87720150 bp, + strand Genetic Position: Chr1, 44.44 cM
• Alliance: Atg16l1^tm3.1Umr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:308892
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted to flank exon 2. An frt-flanked neomycin selection cassette was removed via FLP-mediated recombination in the germline. (J:308892)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atg16l1 Mutation: 47 strains or lines available

References

• Original: J:308892 Wang Y, et al., Non-canonical autophagy functions of ATG16L1 in epithelial cells limit lethal infection by influenza A virus. EMBO J. 2021 Mar 15;40(6):e105543
• All: 1 reference(s)