Eed^tm1.1Hko
Targeted Allele Detail

Summary

• Symbol: Eed^tm1.1Hko
• Name: embryonic ectoderm development; targeted mutation 1.1, Haruhiko Koseki
• MGI ID: MGI:7278694
• Synonyms: Eed^fl
• Gene: Eed Location: Chr7:89603862-89630184 bp, - strand Genetic Position: Chr7, 50.42 cM
• Alliance: Eed^tm1.1Hko page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:324262
• Parent Cell Line: M1/M-1 (ES Cell)
• Strain of Origin: (129 x C57BL/6)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 3 was flanked by loxP sites. An frt-flanked neomycin selection cassette was removed via FLP1-mediated recombination in the germline. (J:324262)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Eed Mutation: 117 strains or lines available

References

• Original: J:324262 Sugishita H, et al., Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes. Nat Commun. 2021 Sep 9;12(1):5341
• All: 2 reference(s)