Unc13a^tm1.1Bros
Targeted Allele Detail

Summary

• Symbol: Unc13a^tm1.1Bros
• Name: unc-13 homolog A; targeted mutation 1.1, Nils Brose
• MGI ID: MGI:7276178
• Synonyms: Munc13-1^fl
• Gene: Unc13a Location: Chr8:72079356-72124418 bp, - strand Genetic Position: Chr8, 34.43 cM, cytoband B3.3
• Alliance: Unc13a^tm1.1Bros page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:324135
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/Ola

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 21 was flanked by loxP sites and an FRT-flanked neomycin selection was inserted and removed via flp-mediated recombination. (J:324135)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Unc13a Mutation: 75 strains or lines available

References

• Original: J:324135 Banerjee A, et al., Molecular and functional architecture of striatal dopamine release sites. Neuron. 2022 Jan 19;110(2):248-265.e9
• All: 4 reference(s)