Khdrbs1^tm1Gqin
Targeted Allele Detail

Summary

• Symbol: Khdrbs1^tm1Gqin
• Name: KH domain containing, RNA binding, signal transduction associated 1; targeted mutation 1, Gangjian Qin
• MGI ID: MGI:7266287
• Synonyms: Sam68^flox
• Gene: Khdrbs1 Location: Chr4:129596957-129636096 bp, - strand Genetic Position: Chr4, 63.34 cM
• Alliance: Khdrbs1^tm1Gqin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:324047
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The targeting vector is designed to insert a loxP site upstream of exon 5. A neomycin resistance cassette, followed by a second loxP site, was inserted downstream of exon 8. (J:324047)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Khdrbs1 Mutation: 32 strains or lines available

References

• Original: J:324047 Qiao A, et al., Sam68 promotes hepatic gluconeogenesis via CRTC2. Nat Commun. 2021 Jun 7;12(1):3340
• All: 2 reference(s)