Rnf146^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rnf146^em1Cya
• Name: ring finger protein 146; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7264806
• Synonyms: Rnf146^em1Cgen
• Gene: Rnf146 Location: Chr10:29220172-29238438 bp, - strand Genetic Position: Chr10, 16.6 cM, cytoband A4
• Alliance: Rnf146^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• TALEN mediated recombination created a mutation in exon 3. (J:323817)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf146 Mutation: 20 strains or lines available

References

• Original: J:323817 Sheng Z, et al., The RING-domain E3 ubiquitin ligase RNF146 promotes cardiac hypertrophy by suppressing the LKB1/AMPK signaling pathway. Exp Cell Res. 2022 Jan 1;410(1):112954
• All: 1 reference(s)