Phf14^em1Hzo
Endonuclease-mediated Allele Detail

Summary

• Symbol: Phf14^em1Hzo
• Name: PHD finger protein 14; endonuclease-mediated mutation 1, Huda Y Zoghbi
• MGI ID: MGI:7264373
• Gene: Phf14 Location: Chr6:11907808-12081204 bp, + strand Genetic Position: Chr6, 5.01 cM, cytoband A2
• Alliance: Phf14^em1Hzo page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 3 was deleted by using two guide RNAs (5-AGCTATTTGATATAAATCAG-3 and 5-AGATGCTAACTGGCAAAGAG-3) through CRISPR/Cas9 genome editing technology. (J:323645)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Phf14 Mutation: 66 strains or lines available

References

• Original: J:323645 Zhou J, et al., Disruption of MeCP2-TCF20 complex underlies distinct neurodevelopmental disorders. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2119078119
• All: 1 reference(s)