Tg(TcraCRP,TcrbCRP)1Lukl
Transgene Detail

Summary

• Symbol: Tg(TcraCRP,TcrbCRP)1Lukl
• Name: transgene insertion 1, Ludger Klein
• MGI ID: MGI:7263365
• Synonyms: TCR-Dep, Tg(TcraCRP,TcrbCRP)1Lk
• Transgene: Tg(TcraCRP,TcrbCRP)1Lukl Location: unknown
• Alliance: Tg(TcraCRP,TcrbCRP)1Lukl page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: Transgenic TCR alpha and beta chain (co-inserted) encoding for an MHC class II (I-Ab) restricted TCR specific for human C-reactive protein (amino acids 89-101). The TCR is referred to as TCR-Dep. (J:312519)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:312519 Klein L, et al., CD4 T cell tolerance to human C-reactive protein, an inducible serum protein, is mediated by medullary thymic epithelium. J Exp Med. 1998 Jul 6;188(1):5-16
• All: 1 reference(s)