Scgb1a1tm1.1(Cicre)Thbr
Targeted Allele Detail
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Symbol: |
Scgb1a1tm1.1(Cicre)Thbr |
Name: |
secretoglobin, family 1A, member 1; targeted mutation 1.1, Thomas Braun |
MGI ID: |
MGI:7263084 |
Synonyms: |
CCSP-2A-mCherry-2A-iCre-C |
Gene: |
Scgb1a1 Location: Chr19:9061006-9065320 bp, - strand Genetic Position: Chr19, 6.05 cM, cytoband A
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Alliance: |
Scgb1a1tm1.1(Cicre)Thbr page
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Allele Type: |
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Targeted (Epitope tag, Recombinase, Reporter) |
Mutation: |
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Insertion
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Scgb1a1tm1.1(Cicre)Thbr expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Scgb1a1 (MGI:98919) |
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Mutation details: Mice were generated by inserting a 2A sequence, mCherry, 2A sequence, and the C terminal 36 amino acids of the DnaE split intein sequence from Nostoc punctiforme (Npu) fused to the C-terminal fragment of improved cre (iCre) recombinase (aa 105-343), FLAG tag, and Frt-flanked neomycin resistance cassette immediately in front of the stop codon of Scgb1a1 coding sequence by homologous recombination. The Frt-flanked neomycin resistance cassette was removed by crossing with hACTB-Flpe deleter mice.
(J:323339)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Scgb1a1
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Scgb1a1 Mutation: |
26 strains or lines available
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Original: |
J:323339 Salwig I, et al., Bronchioalveolar stem cells are a main source for regeneration of distal lung epithelia in vivo. EMBO J. 2019 Jun 17;38(12):e102099 |
All: |
1 reference(s) |
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