Nbea^em1Kili
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nbea^em1Kili
• Name: neurobeachin; endonuclease-mediated mutation 1, Manfred W Kilimann
• MGI ID: MGI:7262988
• Gene: Nbea Location: Chr3:55532616-56091122 bp, - strand Genetic Position: Chr3, 26.61 cM
• Alliance: Nbea^em1Kili page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Nucleotide substitutions
• Mutation details: CRISPR/Cas9 technology generated a leucine to alanine substitution at amino acid 1085 (L1085A). This mutation abolishes the binding activity of Nbea for the catalytic subunit of protein kinase A. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nbea Mutation: 139 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)