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Hlfem1Bcgen
Endonuclease-mediated Allele Detail
Summary
Symbol: Hlfem1Bcgen
Name: hepatic leukemia factor; endonuclease-mediated mutation 1, Biocytogen LLC
MGI ID: MGI:7262731
Synonyms: HlftdTomato
Gene: Hlf  Location: Chr11:90227362-90281721 bp, - strand  Genetic Position: Chr11, 55.03 cM
Alliance: Hlfem1Bcgen page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Reporter)
Mutation:    Insertion
 
Mutation detailsCRISPR/Cas9 genome editing technology was used to insert a 2A-tdTomato expression cassette into the 3' UTR of Hlf gene. (J:312489)
Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hlf Mutation:  15 strains or lines available
References
Original:  J:312489 Tang W, et al., Hlf Expression Marks Early Emergence of Hematopoietic Stem Cell Precursors With Adult Repopulating Potential and Fate. Front Cell Dev Biol. 2021;9:728057
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory