Prmt7^tm1.1Baos
Targeted Allele Detail

Summary

• Symbol: Prmt7^tm1.1Baos
• Name: protein arginine N-methyltransferase 7; targeted mutation 1.1, Shilai Bao
• MGI ID: MGI:7261452
• Synonyms: Prmt7^flox
• Gene: Prmt7 Location: Chr8:106937686-106978326 bp, + strand Genetic Position: Chr8, 53.11 cM
• Alliance: Prmt7^tm1.1Baos page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:317594
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 5 was flanked by loxP sites and an FRT-flanked neomycin selection cassette. The Pgk-Neo cassette was removed by mating with CAG-Flp mice. (J:317594)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prmt7 Mutation: 39 strains or lines available

References

• Original: J:317594 Ying Z, et al., Histone Arginine Methylation by PRMT7 Controls Germinal Center Formation via Regulating Bcl6 Transcription. J Immunol. 2015 Aug 15;195(4):1538-47
• All: 2 reference(s)