Thra^tm2Ffla
Targeted Allele Detail

Summary

• Symbol: Thra^tm2Ffla
• Name: thyroid hormone receptor alpha; targeted mutation 2, Frederic Flamant
• MGI ID: MGI:7261434
• Synonyms: ThraTAG
• Gene: Thra Location: Chr11:98631539-98659832 bp, + strand Genetic Position: Chr11, 62.58 cM, cytoband D-E
• Alliance: Thra^tm2Ffla page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:274584
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Epitope tag)
• Mutation: Insertion
• Mutation details: The targeting construct inserts a TRalpha1 fused with protein G and Strepavidin binding protein (GS) after a floxed stop cassette. (J:274584)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Thra Mutation: 39 strains or lines available

References

• Original: J:274584 Hirose K, et al., Evidence for hormonal control of heart regenerative capacity during endothermy acquisition. Science. 2019 Apr 12;364(6436):184-188
• All: 2 reference(s)