Xpr1^tm1.1Frsv
Targeted Allele Detail

Summary

• Symbol: Xpr1^tm1.1Frsv
• Name: xenotropic and polytropic retrovirus receptor 1; targeted mutation 1, Dmitri Firsov
• MGI ID: MGI:7261304
• Synonyms: Xpr1^lox
• Gene: Xpr1 Location: Chr1:155151447-155293161 bp, - strand Genetic Position: Chr1, 66.49 cM
• Alliance: Xpr1^tm1.1Frsv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:292951
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The targeting construct contains a loxP site upstream of exon 2 and a second loxP site downstream of exon 2. The construct also includes an FRT-flanked neomycin cassette, which is removed with a self-excising flp recombinase included in the construct. (J:292951)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Xpr1 Mutation: 38 strains or lines available

References

• Original: J:292951 Ansermet C, et al., Renal Fanconi Syndrome and Hypophosphatemic Rickets in the Absence of Xenotropic and Polytropic Retroviral Receptor in the Nephron. J Am Soc Nephrol. 2017 Apr;28(4):1073-1078
• All: 1 reference(s)