Bhlhe40^tm1.1Maha
Targeted Allele Detail

Summary

• Symbol: Bhlhe40^tm1.1Maha
• Name: basic helix-loop-helix family, member e40; targeted mutation 1.1, Ganapati H Mahabeleshwar
• MGI ID: MGI:7261229
• Synonyms: Bhlhe40^fl
• Gene: Bhlhe40 Location: Chr6:108637590-108643886 bp, + strand Genetic Position: Chr6, 49.85 cM, cytoband E-F1
• Alliance: Bhlhe40^tm1.1Maha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:323045
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 4 was floxed and an FRT flanked neo cassette was inserted via homologous recombination. Flp mediated recombination removed the neo cassette. (J:323045)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bhlhe40 Mutation: 53 strains or lines available

References

• Original: J:323045 Zafar A, et al., BHLHE40 promotes macrophage pro-inflammatory gene expression and functions. FASEB J. 2021 Oct;35(10):e21940
• All: 1 reference(s)